Molecular Biology Software
Don’t lose data to the disconnect
A unified project workflow
Core Features & Integrated Benefits:
Native Plasmid Map Software
Visualise and manipulate DNA sequences within the same interface as your lab notes. This eliminates "tab-jumping" and ensures your most current design is always the one being referenced by the team.
Precise Fragment Isolation
Identify restriction sites for a comprehensive list of enzymes to generate new DNA fragments in silico. Lab Thread automatically generates the isolated fragment as a new sequence file, complete with annotated history and overhang details, ready to be used in downstream cloning, sequencing or PCR protocols.
Intelligent DNA Primer Design
Design DNA primers with automated melting temperature calculations and store them with full metadata. Primers are automatically available for selection in your PCR protocols, removing the need for manual data entry.
Digital Gel Simulations
Simulate restriction digests, ligations and PCR reactions, and visualize them on digital gel ladders. Prevent wasted lab time on non-viable constructs.
Intuitive Ligation & DNA Assembly
Drag and drop your isolated fragments into a destination vector to model complex multi-fragment assemblies. The software automatically handles sticky-end and blunt-end compatibility, generating the final plasmid map while maintaining a digital connection between the original “parent” plasmids and new “child” constructs for easy lineage tracing and troubleshooting.
Direct Sequence Attribution
Link sequences directly to physical samples in your inventory for an unbreakable "Origin Story" that ensures total traceability for audits or publications.
Seamless Alignment & Visualisation
Compare sequencing results against your original designs to instantly identify mutations or clones that match your design intent without leaving the platform.
Structural Integrity for your Science
Connected Designs
Link DNA sequences and plasmid maps directly to your physical inventory.
Institutional Memory
Protect against staff turnover with a unified digital thread.
Audit-Ready Records
Accelerate towards milestone based funding with traceable records that satisfy regulators.
Searchable Assets
Turn a series of experiments into a searchable and reproducible database.
Everything you need to know
By default, notifications will be highlighted within the app; click on the bell icon in the top right to see new notifications. Additionally, you will receive actionable notifications (such as a task assignments, sharing designs, mentions or requests for approval) via email, allowing you to take action directly from your inbox.The system will also automatically send you a “round up” email highlighting any unactioned review requests at the beginning of each week.
Yes. Lab Thread’s molecular biology software allows you to import standard file formats, ensuring you can visualize your existing plasmid maps and DNA primer libraries without losing previous work.
The platform includes intelligent DNA primer design with automated melting temperature calculations. Once designed, primers are automatically available for selection in your PCR protocols, eliminating the risk of transcription errors.
Yes. When you isolate a fragment via restriction digest, Lab Thread saves it as a distinct sequence. This allows you to build a "parts library" of inserts and backbones that can be used across multiple ligation protocols or shared with your team.
The platform automatically identifies 5' and 3' overhangs created during your simulated digest. It will only allow ligation between compatible ends, preventing in silico mistakes that would lead to failed experiments at the benc
Absolutely. Every ligated construct maintains a digital lineage. You can "click back" through the Digital Thread to see the exact PCR fragments or restriction digests used to create the final sequence, including the original source plasmids.
Yes. A core benefit of our unified architecture is direct sequence attribution. You can link any plasmid map or sequence directly to physical samples in your repository, creating an unbreakable "Origin Story" for every vial.
The software allows you to simulate restriction digests, ligations, and PCR reactions. You can visualize these results on digital gel ladders to confirm your strategy before committing your time or expensive reagents.
Yes. Lab Thread includes a native Molecular Biology Suite for in silico DNA and plasmid design. Because it is integrated, your designs link directly to restriction digest protocols and ELN records, removing the need for separate subscriptions.
Lab Thread improves reproducibility by standardizing data capture and providing a robust search function. By tethering plasmid designs, experimental protocols and data analysis to every sample, researchers can instantly retrieve the specific protocols and designs used by past staff or students, preventing knowledge loss.
Yes. Lab Thread subscribers are eligible for a 10% discount on all purchases from IDT (Integrated DNA Technologies). Once you have completed your free trial and started your paid (or free academic) plan, click on your initials in the top right hand corner of the app, and select Subscription to find the discount code.
